At Northern Westchester Hospital, we are committed to providing leading-edge treatments and clinical trials close to home. Our patients can benefit from major medical advancements previously found in big city hospitals, now in the comfort of our own community.
Click on a link below to view clinical trials at Northern Westchester Hospital for:
We continue to expand the availability of clinical trials in Westchester, New York and Fairfield, CT. For more information on Northern Westchester Hospital Clinical Trials, click CONTACT US on the left, or call the Clinical Trials Director, Dr. Joshua Fink, at 914.666.1366.
What: The Dana-Farber Young and Strong Program focuses on the needs of young women who have been diagnosed with breast cancer. This is an educational and supportive study and does not include any medications.
Who: Women between the ages of 18 and 45 who have been diagnosed with stage I, II or III breast cancer within the last three months.
Why: The purpose of this program is to address the gaps in care for young women with breast cancer as part of a larger effort to better understand breast cancer and to improve the care and outcomes for our younger patients. This study examines whether educational interventions focusing on issues unique to young women with breast cancer, combined with healthy lifestyles, can help to improve the care of young breast cancer patients. The investigators believe that concerns related to fertility, including body image, sexual dysfunction, and physical activity, can be addressed early in order to improve the satisfaction of care and quality of life for young women.
What: The NSABP B47 study is a trial of adjuvant therapy comparing chemotherapy alone to chemotherapy plus trastuzumab in women with node-positive or high-risk node-negative HER2-low-invasive breast cancer.
Who: This study is designed for women who are 18 years or older that are not pregnant or nursing. To be eligible, the patient must have undergone either a total mastectomy or breast-conserving surgery (lumpectomy) (patients who have had a nipple-sparing mastectomy are eligible).
Why: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) and giving chemotherapy after surgery may kill more tumor cells. Monoclonal antibodies, such as trastuzumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread and others find cancer cells and help kill them or carry cancer-killing substances to them. It is not yet known whether combination chemotherapy is more effective with trastuzumab in treating breast cancer. The purpose of this study is to determine if adding a targeted therapy, trastuzumab, to standard treatment with chemotherapy for early stage, HER2-low breast cancer, will prevent breast cancer from returning.
Join Us: To see if you, or someone you may know, fit the criteria for one of our breast cancer studies, please contact the Clinical Trials Coordinator at Northern Westchester Hospital: 914.666.1366, or click CONTACT US above.
What: The DCVax-L study is evaluating an experimental vaccine for its effectiveness in treating Glioblastoma brain tumors.
Who: This study is designed for patients diagnosed with a Glioblastoma tumor – a specific type of cancerous brain tumor.
Why: The DCVax-L study is evaluating an experimental vaccine derived from a patient’s own white blood cells that is believed to work with the patient’s immune system to target brain cancer cells.
Join Us: To see if you, or someone you may know, fit the criteria for the brain tumor study, please contact the Clinical Trials Coordinator at Northern Westchester Hospital: 914.666.1366, or click CONTACT US above.
What: The MEAL study, sponsored by the National Cancer Institute, focuses on whether a man's nutrition and diet can contribute towards the progression of prostate cancer.
Who: The MEAL study is designed for men who have been diagnosed with prostate cancer and have been placed on active surveillance, also known as the watch and wait approach. These men have not had chemotherapy, radiation or surgery.
Why: The MEAL study is designed to test whether a high-vegetable diet will lower the risk for prostate cancer progression compared to a “standard” diet. The MEAL study is crucial to our understanding of the possible relation between consumption of foods and food groups and the progression of prostate cancer.
Join Us: To see if you, or someone you may know, fit the criteria for the MEAL study, please contact the Clinical Trials Coordinator at Northern Westchester Hospital: 914.666.1366, or click CONTACT US above.
What: A phase III randomized study that seeks to compare ofatumumab and rituximab in the treatment of follicular non-Hodgkin's lymphoma.
Who: This study is designed for adults 18 years or older with follicular non-Hodgkin's lymphoma who have relapsed at least six months after completing their last prior treatment of rituximab-containing therapy.
Why: Rituxan (rituximab) is the current standard of care for patients with slow-growing lymphomas, such as follicular non-Hodgkin's lymphoma. Although Rituxan is a highly targeted and well-tolerated lymphoma treatment, the remission rate is lower. Ofatumumab has induced remissions in patients with similar conditions, but has not yet been studied in follicular lymphoma. The HOMER study seeks to determine whether ofatumumab alone can achieve improved outcomes.
What: The CALGB trial is a Phase II randomized trial comparing the use of high and low doses of ofatumumab for previously untreated patients with follicular non-Hodgkin’s lymphoma to determine whether higher or lower doses can achieve improved outcomes in patients with low-grade follicular NHL.
Who: This study is designed for adults 18 years or older with follicular non-Hodgkin’s lymphoma who have been previously untreated. Those that are pregnant or nursing are not eligible.
What: This randomized phase II trial studies how well giving azacitidine works with or without lenalidomide or vorinostat in treating patients with higher-risk myelodysplastic syndromes or chronic myelomonocytic leukemia.
Who: This study is designed for adults 18 years or older that have morphologically confirmed diagnosis of myelodysplastic syndromes (MDS) or chronic myelomonocytic leukemia (CMML).
Why: Drugs used in chemotherapy, such as azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells or stopping them from dividing. Lenalidomide may stop the growth of cancer cells by stopping blood flow to the cancer. Vorinostat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. It is not yet known whether azacitidine is more effective with or without lenalidomide or vorinostat in treating myelodysplastic syndromes or chronic myelomonocytic leukemia.
Join Us: To see if you, or someone you may know, fit the criteria for the S1117 study in leukemia, please contact the Clinical Trials Coordinator at Northern Westchester Hospital: 914.666.1366, or click CONTACT US above.
What: 402-C-323 is a pain management study which seeks to evaluate the effectiveness and the rate of absorption of a single injection femoral nerve block with Liposome Bupivacaine for postsurgical pain in patients undergoing total knee replacement surgery.
Who: This study is for patients 18 years or older who are undergoing total knee replacement surgery under general or spinal anesthesia.
Why: The 402-C-323 study seeks to determine the efficacy of a single injection femoral nerve block with three dose levels of liposome bupivacaine to manage post-operative pain for patients after a total knee replacement procedure.
Joshua Fink, MD, is the Medical Director of the Clinical Trials Program at Northern Westchester Hospital, Mt. Kisco, NY.
Jonathan Goldberg, MD, is the Medical Director of the Cancer Clinical Trials at the Cancer Treatment and Wellness Center at Northern Westchester Hospital.
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